Dr. Marcus O'Mahony

Having obtained his PhD in Chemistry from the University of Limerick working within the Synthesis and Solid-State Pharmaceutical Centre, Marcus has contributed to R&D in both academic and industrial environments for over 10 years, and he now uses that experience to support PMTC industry partners in their strategic research. 

For his postdoctoral research, Marcus contributed to the Novartis-MIT Centre for Continuous Manufacturing as well as the DARPA Pharmacy on Demand project in the Department of Chemical Engineering at MIT, later joining Vertex Pharmaceuticals and worked within formulation development where, as a subject matter expert, he was the process development lead in the technical transfer of a new drug product from early clinical batch manufacture to the commercial continuous manufacturing platform. He has contributed to fundamental unit operation understanding and has also led a cross-functional data science initiative while at Vertex.

Marcus has experience in leading projects within industry, attracting funding in an academic setting as well demonstrating the commercial potential of his research work. His research interests include statistical analysis and modelling in continuous and intensified processing technologies, crystallization technology and the engineering of particulate solids and powders. His publications and patent record include a book chapter, 13 journal articles and 4 patents (2 of which have been licensed) in the area of pharmaceutical particle engineering and continuous manufacturing. Marcus is passionate about supporting and developing new technologies in pharmaceutical manufacturing.

Areas of Expertise:

• Multivariate Analysis and PAT
• Data Processing and User Interface Development
• Continuous Manufacturing including control strategy development (OSD)
• Continuous Loss-In-Weight Feeding
• Tableting and Compaction
• Powder Characterisation
• Particle Engineering
• Crystallization
• Continuous Crystallization

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